How do I ask a friend if I can give him an enema?

You might ask if he has ever had an enema, adding that you had one recently, and see how he reacts. (at this point, he would not know if it was for medical procedure, or for fun.) this way, you give him a reason and opportunity to ask questions about how/why you had one, what it was like, and possibly reveal his own experiences. If this conversation seems to proceed favorably, then you could work it around to asking to give him one, or for him to give one to you! Everything remains fairly neutral, awaiting his reaction, if approached this way!

How many guys here play with other guys. Guy giving guys enemas seems very erotic we both know what feels good and where !

The guys that I enjoy giving enemas to are not my friends, I would find it difficult to approach someone who is. Friend.

The guys that I enjoy giving enemas to are not my friends, I would find it difficult to approach someone who is. Friend.

I agree.

Trying to engage a friend to do enemas could irreparably damage your friendship relationship in the same manner that having sex with a friend could damage a friendship.