Have you ever had a glycerin suppository not work?

As others have replied, glycerin suppositories will only work if there is a (probably) hardened bowel movement in or close to the rectum, which would have been ready to be expelled. If there is nothing close to or in the rectum, the suppository (one or more) will have little effect on producing a bowel movement for you.

@KennyT But if you keep the melted glycerin in your rectum, and some waste descends into your rectum, which may happen a while after you had the suppository, then you will feel a strong need to evacuate. Delayed effect!

It happens to my girlfriend. She needs more than 2 sometimes.

Well sort of, I've been using a lump of saddle soap which I think can be better than a glycerin suppository. But I'm sure my body gets used to them, so doesn't work well after sometime. So it's back to glycerin suppository, til they don't work, and so on.

New to suppositories and for those who haven’t tried them they are affordable, effective and readily available fun at your local drugstore. Have only tried Fleet so far.

Another time when glycerin did not work.

I had a bike accident 15 years ago, and had to get surgery on my leg. They gave me painkillers. I realized that I had not moved my bowels since the accident. Some oral laxative and glycerin suppositories were tried, to no avail. Finally, my wife ended up giving me an enema to unclog the situation. First time I was that much constipated.

If for experimenting on myself then yes I have taken fews . But if for real use like constipation then no

Glycerin suppositories do not work for me, they have no effect. The liquid ones work in about 5 minutes. If necessary, I use Dulcolax suppositories and in 10 minutes I am on the toilet.

I remember when I was about 12 years old I didn't poop for several days, I started having cramps and my mother put a glycerin suppository. It had no effect, but the pain stopped. Hours later, my mom put in two more glycerin suppositories, pushing deep. This time it worked.

Yes, this happened. It seems I get very constipated easily if taking opiate painkillers, and in that case just taking a glycerin suppository won't do it. Fortunately, in cases I took opiates, the pain subsided rather fast so I was able to stop them early. I however had to take an enema in one occasion, at least to ease the stress of not having pooped for a number of days.

Well they do work, but i think their effectveness weares off if you use enough as i do for fun, so i switch to saddle soap which def works for a time, then back to glycerine supps and so on.........just what happens with me, maybe not everone, ccomments please.