Glycerine is easy to get cleaned out of the bag. It is NOT an oil and is water soluble.I use glycerine in the bag frequently--it is no problem. I like it mixed in with the water.The precipitate is what I said is difficult to clean out of the bag and hose if you mix soap, glycerine and epsom salts.Epsom salts and/or glycerine will both give return trips to the toilet. These return trips ARE NOT the result of retained water. It is due to epsom salts and glycerine, either alone or together that draws water into the colon for 12-24 hours after the enema.