I totally agree with @ProV1 and @LisaK: enema pleasure and anal-penetration pleasure are two totally different things. They don't have to go together, although they do for me. I very much enjoy them both in every form, (except not yet anal penetration by a man's penis--which is on my bucket list.) I often enjoy orgasm-inducing anal-penetration pleasure right after enjoying an hour of enema pleasure with orgasm denial.
I do understand @LisaK's love of enema pleasure and distaste for anal-penetration pleasure. Sometimes I'll spend an hour giving myself enemas solely for the enema pleasure and a good orgasm with no thought of anal-penetration pleasure. If @LisaK want's to enjoy enemas this way all the time, and only derive anally induced sexual pleasure from enema pleasure, I can understand and respect that. No doubt many men also enjoy enemas that way too.
I love @Lora C's description of the deep intimacy and trust between two people giving each other enemas. I love when my wife and I do enemas together. It's every bit as special a time together as sex is for us. Our shared enemas don't always lead to sex, but they do a lot of the time, especially when Pam's enema is orgasmic and mine isn't.
Pam and I, just as @pmoi enjoys, love being plugged for sex after enemas. (We also enjoy anal sex with just me plugged.) I think @Lora C likes being plugged for sex too, or was it @Ms Lila who liked that? Sex with the woman plugged feels so good for both lovers--it's a tighter feeling, the man can feel the woman's butt plug from inside her vagina, and the woman can feel the man's penis inside her both vaginally and anally according to Pam. Giving each other enemas makes us want to enjoy those feeling and helps us to enjoy them more.
There are many other ways enema pleasure and anal-penetration pleasure tend to go together. I think most people understand this to some extent, so I don't think the social stigmas of anal sex and enemas are that different. Here are some more ways they go together: (1) both can be primary orgasm inducers with merely secondary genital stimulation or even zero genital stimulation at times. (2) Enemas are often used to clean out the rectum and colon to prepare and stimulate them for anal-penetration pleasure soon after. (3) Fat, long, or fat+long enema nozzles, retention plugs, balloon nozzles, or colon tubes can simultaneously produce both enema pleasure and anal-penetration pleasure. To fully appreciate this, have your lover gently fuck you anally with a long fat enema nozzle while the warm water is slowly flowing into you at the same time he or she gently massages your genitals. (4) Enema pleasure tends to make enema lovers who like anal-penetration pleasure crave that pleasure right after an enema session. I know it does that for me, and I suspect this is common for male and female enema lovers.