OPINION on combination of suppositories

Hello ,i was wondering if anyone tried a combination of suppositories . I was thinking to combine glycerine with co2 . Do you think it is dangerous and if not would i to worth to try ?

Hi, I have done this many times without any kind of problem, feels good and seems to be no big deal…

Do it. I have done glycerin and bisacodyl a couple of times. For that I usually put the glycerin in first, then 10 mins or so later the bisacodyl. The glycerin softens and lubricates somewhat, then the bisacodyl kicks things out. Not as good as an enema, but still good.

In mixing meds it is always what you are mixing. Manufacturer's info should have drug interactions on it.