Ok, the op did qualify "generally," but even then, there isn't a black or white answer for me. i don't think that just because guys have the same equipment they are therefore in a better position to understand what the suckee likes. In my experience, not everyone likes the same thing or technique. We all have tongues, but we don't all have the same tastes.
My only experience with a woman was with my former wife, and she obviously didn't get into it. It was clear to me that her only goal was to get me aroused so i could pleasure her. But i know that that is not a universal phenomena. Same with guys. Which for me identifies an important component, i.e., is the person i am with really into what they are doing?
i don't care how mechanically capable a guy is, if i don't sense that he is into it, something is missing for me, it's very similar to masturbating. On the other hand, even if the person i am with isn't all that skilled, if they are obviously really into what they are doing, i'm going to end up really enjoying.
In my experience, the two often go together, i.e., those who are really into sucking cock usually have developed a certain amount of skill because part of being into it is the pleasure they bring.
i don't think it really is a question of male or female or knowing the anatomy because we have the parts. i got good at giving my former wife oral sex, mostly because i got a great deal of pleasure giving her pleasure that way. It wasn't a task for me to give her pleasure. Same with the guys i am with. If i have a sense He is not connected or doesn't care about what i am doing, it goes full circle for me and i stop enjoying what i am doing and it becomes a task and i'm sure i'm not as 'good' at it at that point.