It's very hard to put antibiotics into a rectal medium that will enter the bloodstream and be effective on infections. Since the bowel is FULL of bacteria from many strains, an antibiotic supp. may have a local effect on the natural bowel flora. If the patient cannot take the A/B orally, IM or IV is the best route. IV method means the medication starts working in seconds.
One of the previous poster mentioned that Compazine worked on nausea, but they had side effects that were difficult. I used to be able to take Compazine for nausea, but after awhile, I started experiencing "extrapyramidal" side effects. I got nervous and the dead giveaway was when I started getting an involuntary muscle contractions in my jaws and around the mouth. This side effect is often seen in psychiatric patients taking Thorazine, Stelazine for mental illness. (Notice that these two drugs sound a lot like Compazine). In fact, they are just the big brothers of Compazine, so it's not surprising that Compazine can also cause extrapyramidal s/e and "tardive dyskinesia".
If you can't take Compazine for nausea, you should be able to take Tigan rectally. It works fairly well. Or, you can get an Rx for Zofran nasal spray. Zofran can also be given by
injection, usually IV.
DO NOT take aspirin tabs., rectally. The ASA in them will irritate the rectal tissues and frequent use could cause bleeding. Ever heard about frequent aspirin users developing stomach ulcers?
I believe that Vicki mentioned not using Vaseline as a lube to insert a suppo. This is correct. Coating a suppo. with a petroleum based lube can prevent it from dissolving in the rectum. Use a water based lube, or just wet the suppo and insert it slowly.
My statements here may be subject to some corrections from the medical professionals on Zity. I have sold many of these medications over the years, but I am not a physician.