Medicated suppositories

Ok lots of talk about laxatives and some forms of punishment via suppository.

Would love to hear about experiences with medicated suppositories... I've had tylenol via suppository and actually cough medication (in French Canada and highly effective btw). I'm aware of anti-nausea. What else?

I'd like to hear about these experiences too. I take a lot of medications and it's difficult for me to swallow all the pills. I've wondered if any of them could be taken in suppository form.

I do not have any experiences to share, but you can get an idea of whether a medication is made in suppository form from a website like Medscape (http://reference.medscape.com).* Just look for the abbreviation PR - per rectum. There is also a subspecialty in pharmacy called compounding, and one of the things compounding pharmacists do is to provide medications in forms other than what is manufactured by the big-scale pharmaceuticals.

*Disclaimer: I'm not a health care professional; nothing that I say or suggest reading should be taken as medical advice. (On the other hand, I do health care research so I take these things very seriously!)

I have gotten tylenol supposotories. I have also had some types for anti nausia after a procedure or operation. I know I had to get them because the codeine I was given made me sick. Also phenergran (spelling?) after wisdome teeth. The pain killers made me sick to my stomach as well and the only way to get the anti nausia meds in my system was rectally.

I have taken Tylenol suppositories before only because a pharmacist advised me to when I said I get migraines and oral meds do not help them and also because my migraines make me really nauseous. so when I get a migraine I take the Tylenol suppositories and it works and takes my headache away. for instance one day I had a migraine and was out shopping and had to take oral Tylenol and then later my migraine got way worse, but if I am at home and get a migraine I will take the Tylenol suppositories and within say 2 hours or so my migraine is gone and I feeling way better. so I prefer Tylenol suppositories over oral Tylenol anyday

When I need an aspirin - ibuprophin - I woild like to take it anally. Can I get good results by sticking the pill up my ass or do I have to crush it and put it in suppository form?

I Googled this question and most people who tried it found that the tablet never dissolved in their butt, probably because there's not enough fluid to make that happen.

Your best bet is to purchase Tylenol suppositories from a store. I would not think it is a good idea to put the aspirin tablet itself into your ass. it would probably irritate your colon so much that you might start bleeding. I am sure those with medical knowledge will have more to add on this topic.

Please use COMMON SENSE

I've had Compazine and Phenergan and Tylenol (acetaminophen) rectally. Compazine and Phenergan were for nausea, including during my first pregnancy. I had a terrible reaction to Compazine so my doctor switched to Phenergan, which was a good drug but made me sooo sleepy. Tylenol suppositories help with headaches and moderate pain when I'm sick and have a creepy stomach.

Like I said before I take Tylenol suppositories for my migraines because they work way better for me then oral meds do. suppositories also work faster then oral meds. I take oral meds for a headache and still have it 4 hours later and when I take a suppository for the pain it is gone in about 2 hours or less. so I prefer to take suppositories for the pain when I get any. now if I am out and about like at school or shopping and I get a headache I do take oral meds then but if I am at home then I take suppositories as they are way better then oral meds. Vicki I never had suppositories for nausea but I wanted to try them as my migraine's leave me really nauseous. is that something that you can get over the counter like Tylenol suppositories or is it something that you need to ask a doctor for? If the suppositories for nausea need to be gotten by a doctors script then I do not know about getting it because I am a person that feels weird asking my doctor for things like that. I guess it is common but I feel weird for asking them for things like that so can you get it over the counter or is it by prescription only? thanks in advance for the help.

The ER gave me a Cafergot suppository years ago for a terrible migraine headache. They were even kind enough to send me home with a prescription for them! It along with a FIORINAL (butalbital, aspirin, and caffeine) capsule really knocked the headache (and me) out quick! I believe it is a vascular dilator and it made me feel like I was floating. I still take the Fiorinal for my migraine headaches, but have never found another doctor that would prescribe the Cafergot again.

Does anyone by chance know if they make antibiotics' in suppository form? I am asking because I have pneumonia right now and I was given an oral antibiotic for it and the last few times I have taken my antibiotic I have gotten sick from coughing and then lost my antibiotic from getting sick and I can't keep losing it that way. so I was thinking about suppositories as they seem to work better for me. but I am not sure if you can get antibiotics in suppository form or not, someone told me you can but I am not sure. so do antibiotics come in suppository form?

Medicated suppositories for nausea and vomiting are prescriptions. Acetaminophen (Tylenol) for headache is OTC but you'll likely have to ask at the pharmacy cuz the suppositories are usually kept cold. As I posted earlier, I've had Compazine and Phenergan rectally, although both are available (I think) in pill form. I know Compazine is also given by IM injection, as I've had a sore bottom to prove it. I've been with our family doctor for years, and if I'm ever that sick and can't keep anything down, they'll always ok Phenergan suppositories for me if I need them. However, be warned that they will likely make you sleepy. As far as antibiotics, I've never taken one rectally, so I'm not the one to ask. Years ago if I needed an antibiotic, it usually meant a shot in the butt. Nowadays, it's mostly oral meds -- at least with my doc.

Momofcutecat,

I am not aware of any commercially available antibiotic suppository. However, a compounding pharmacy can make almost anything into a suppository. Since it takes their time, it will not covered by insurance, and you can also get inconsistent absorption through the rectum. But if you vomiting the oral form, you are getting inconsistent absorption there also. It would be a matter of talking your doctor into OK'ing it and pharmacist into doing it. I understand in Europe many medicines are delivered by suppository. Maybe some members from Europe can add to this discussion. Good luck.

The British NHS lists a product on its website (http://www.nhs.uk/medicine-guides/pages/MedicineOverview.aspx?condition=Bacterial%20infections&medicine=metronidazole&preparation=Metronidazole%20500mg%20suppositories), but I suppose that the information might be outdated and it may no longer be on the market. According to other sites, they are known as Flagyl suppositories and manufactured by Winthrop or its generics brand. However, I could neither find any online pharmacies that offer them, nor any information on the manufacturer's website.

Era13,

Flagyl is commonly used for vaginal infections and is available orally and as a vaginal gel. I am not aware that there are any commercially available for either vaginal or rectal use.

With some of the Smart Asses I know, I have threatened to make my big metal tool box into a Highly "Medicated" Suppository administered with a size 13 EEE Boot Chaser (Applicator?)!

There are a range of other medicines taken as suppositories. you can get Valium as a suppository, and this is quite large. I find it acts quickly and has quite an effect. It works best if taken regularly as per prescription, As I am given them when lying down, I can relax as they begin their effect.

I've been given many anti-nausea suppositories. I'd like to try Tylenol suppositories, as oral doesn't seem to have an effect on me.

Suppositories seem to work faster that orally for me, it only takes a few minutes before I notice the effect, but this probably varies between different people. As I am given a sedative lying down, and rarely walk about during the effects I can enjoy them all the better without anyone else noticing. There seems to be a peak a few minutes after, then the effect lasts for several hours. Orally, the effect is rather less and sometimes hardly noticeable at all. Since these are only a children's dose , they are not supposed to be very strong. So I think they are more effective in calming as a suppository.

I have heard of Fever Suppositories... I think I may have received some when I was younger.. :-\\ (Mum was always attending to my bottom for some reason or other.)

Wow. I never knew that medications were available as suppository.

What is the advantage of them being administered this way (besides not being able to swallow pills/liquid or getting sick from oral administration). Does it absorb more quickly? How long would you need to wait for everything to get absorbed?

I am supprised they don't make a viagra type suppository, Or do they? I think it would help get things going. I would sure use them.

The advantage seems to be in many cases a much quicker and more intense action, somethings are less effective going through the entire digestive system I find sedatives are more intense this way, To start with I was not at all keen, but eagerly wait for them because of their rapid pleasant effects. Taken orally they have much less effect. This would of course vary between individuals, but it seems there is a more direct route to the bloodstream and the brain, causing less stomach or bowel upsets, Doses can be smaller, and should be tested to begin at half dose. A flush with a bidet also increase the speed of action as well. I usually only have to wait a few minutes before noticing the effects.

Trying viagra, i would start at half dose,

Those of us of male persuasion who have had urological work done (turp, cystoscope etc.) may have experienced opium and belladonna suppositories for bladder spasms.

The spasms are very uncomfortable/painful and the supp brings almost immediate relief. Especially when giving by a lovely young nurse

They currently have Viagra suppositories for women. They are inserted vaginally to help promote successful in-vitro fertilization.

I don't know what differences there are in the constituents, but I can guarantee there have been guys who have gotten hold of them and popped them up there ass. I would 😃

Viagra as suppository? gosh, they would never get the coffin lid down without sawing a hole in it !! or sawing offf….. err ….

Prob best to start with half a tablet, and not have to move about for a day or so!

Suppositories are much more effective in delivering water soluble medicine. I had a nurse say it makes delivery quicker as it does not depend on the digestion, so a nurse doesn't have to wait around to check effectiveness. Also eating some things stops a lot of medicine working, others need a full stomach because they irritate. and often dosages have to be increased a lot to take this into account. this does not happen with a proper suppositories.

For medical delivery they were once preferred.

When I grew up (1970s) in France suppositories were popular with parents and doctors to give medication to children (and adults, but more for children I think). I don't know why exactly.

So I got lots of them: either prescription drugs after seeing the doctor, either some kind of cough/sore throat medicine that my mom stocked.

They had drawbacks. One is that the medication is diluted in some kind of grease, which used to be cocoa butter at some point then they moved to some synthetic stuff. I don't know exactly what they used during my childhood, but basically that grease ended up seeping off my anus - especially if I farted. So quickly one felt like one had pooped in his pants, with squishy buttocks.

My mom had found a way around this difficulty - she put a panty liner in my briefs after giving me the suppository.

Nowadays, much fewer medications are available in suppository form in France. The only ones I know off-hand are the cough/sore throat medicines and acetaminophen (paracetamol as it is known in France). The grease makes much less of a mess.

As for searching the web for medication that can be taken in suppository form (i.e. compounding, etc), it is easier to search for either 'rectal bio-availability' or 'ROA bio-availability' (ROA is route of administration). The bio-availability is typically shown as a % which is how much of the administered medication makes it to the bloodstream. Typically, the BA (bio-avail) percentages are higher for the backdoor route because of the excellent blood supply back there, the medication goes directly into the bloodstream instead of hitting the liver first, and that there is no stomach acid that breaks down the medicine before it is absorbed like the oral route. There are some medications that need to go to the liver first in order to work properly (called first pass metabolism, typically a lot of the synthetic medicines) but in most cases, if they make it in pill form, they can also make it in a slippery pill form too.

Not intended to be medical advice because I'm not a doctor. Just letting you know what is what if you try to search the web and run across the heavily medical technojargon.

I'm in hospital at the minute have been for the last month almost . I originally had urinary sepsis and now the very painful Steven Johnsons Syndrome has took hold . I've had Paracetomol suppositories for fever and pain , dimenhydrinate suppositories for anti sickness alongside the IM injection of zofran. I find the suppositories work faster than the IV paracetomol and are much more gentle on the stomach.

Best use a non-oil base lubricant when using suppositories. I was on Phenergan early during my two pregnancies, and my pharmacist at the time recommended against using Vaseline. She said the coating would likely delay the med from taking full effect. I've also found that acetaminophen suppositories do work a little quicker for headaches, flu-like pain and fever. Plus, when my husband gives them, being sick (about once a year I come down with something, usually after flying) -- can be more fun. 😃

By the way, just a few thoughts from my personal experience using suppositories. Phenergan 25mg, which I used early-on during my two pregnancies, were good drugs but they can make you really sleepy. I've taken Compazine supps a couple of times. They stopped the vomiting but made me agitated -- just the opposite effect of the Phenergan. I was introduced to Acetaminophen (Tylenol) suppositories by my local pharmacist during the worst flu and highest fever I ever had. The suppositories are OTC and often kept in a fridge or cooler, so you'll need to ask. Don't be shy. Pharmacists and clerks have heard and seen it all. The supps work best with K-Y or Surgilube as a lube, finger cot for comfort in inserting (also for hygiene), and when they are pushed against a "side" inside your bottom and held there for 15 to 20 seconds, they'll begin to dissolve faster.

Hint: It can be a nice "oasis" during an illness if a spouse or partner knows how to give a suppository. Acetaminophen is given each 4 to 6 hours, which means your "nurse" will need to get up and give one during the night. When my husband said he would do that for me at 3AM for a couple of nights straight, these are the "little things" in our marriage that I cherish -- and I have a zillion "little things" to be thankful for.