Blade/Knife play - Scalpels?

Has anyone done any medical roleplays using scalpels before? And if so, how did you go about it? As in "Did you sanitize in any particular way?" "Did you actually make any cuts?" "What sort of context were they said to have been used in?" etc.

I may be interested in eventually doing so with my partner, but after slowly working up to it with safety/prop blades beforehand and obviously with all necessary safety and sanitation precautions. I'd get some disposables for it—ideally the same ones I used in my labs since I'm most comfortable with them—and keep my partner restrained.

Overall, I was wondering if anyone else has any experience with integrating scalpels into medplay so I'll have a better idea of what to expect and possibly get some ideas for scenes.