Bisacodyl added to large enema

Dulcolax tablets have a coating which prevents the tablet from dissolving in acidic environments. The coating is designed to to only slowly dissolve in a pH range of 6.8 to 7.0. The pH of distilled water is 7.0 nominal. It takes over 24 hours for the coating to erode in water at room temperature. Raising the temperature to about 40 degrees C accelerates the rate at which the coating dissolves.

If you want to quickly dissolve the coating on a bisacodyl tablet you can use ordinary baking soda in a small amount of water. The baking soda shifts the pH of water above 7.0. About ½ teaspoon of baking soda in 30 mL of water will yield a pH of about 8.0 which causes rapid breakdown of the protective coating on the tablet. Once the protective coating is removed water rapidly disintegrates the tablet core containing the bisacodyl.

Bisacodyl ( the drug, not the coating) is essentially insoluble in water and settles rapidly in a water solution. Bisacodyl's published solubility is only 3 micrograms per milliliter of water at 37 degrees C. While the tablet core does disintegrate, Bisacodyl rapidly settles in water. That is the reason why Mini-Enemas in squeeze bottles containing bisacodyl require vigorous shaking just before administration, ideally with the patient in a prone position or with knees under the patient raising their buttocks up in the air. The rapidly settling bisacodyl collects around the squeeze bottle opening when inverted and the rush of fluid exiting the bottle drafts the drug from the surfaces it collects upon.

Most of the time you will end up using a bisacodyl suppository. Ideally about 15 minutes before you start the enema itself.

I do it when I get back to the bed after having peed.

I prefer the Fleet bisacodyl mini-enema when it's available.

I use it after I'm in position but before the nozzle insertion.

I never feel the fluid itself going in, but after about 20 minutes, which is usually just about in time for main enema valve opening, I start to feel a hint of having to “go”

If you can get the Fleet Bisacodyl mini enema, that's the best way. If not a bisacodyl suppository or two will work. Just give the suppository about 10-15 minutes to dissolve before doing the main part of the enema!!

@Midas , @paula , I live in Germany, and I looked everywhere (amazon, ebay, also in UK and other countries) but could only find Magic Bullets sold in and shipped from the US, with exorbitant postage (above $20) in addition to the already high price. My conclusion: only available in the US, not in Europe.

@chmajovo

You don' NEED the Magic Bullet suppositories. They are just a convenient way to spike an enema w/ Dulcolax.

One Magic Bullet has the same amount of active ingredients as two Dulcolax pills. Either two of the MB suppositories or 4 well crushed pills, added to a 1500ml of warm water enema, should make the recipient strongly cramp within a half hour. The pooing quickly follows.

@Sean

In my experience, both melted Dulcolax suppositories and crushed pills float on top of the water, and thus will not get where you want them to go. That's why I am interested in the water-soluble variant.

With 20mg of bisacodyl inside, I certainly need not wait half an hour for the cramps and the pooing!

@chmajovo

It's no surprise that ordinary Dulcolax suppositories float on water, because the base material is wax-like. nut, that does not mean the active ingredient does not get into the water.

The pills (and suppositories) are made up several components, only a tiny part of which (the size of a pinhead), is the laxative. You can't tell by looking at the enema solution if it has the Dulcolax or not.

@Midas you can purchase Magic Bullet suppositories on Amazon. From my experience, they are wonderful and typically work very well within 30 minutes.

@sirensong, that's where we purchase ours at 100 at a time. Work wonders and out work anything else out there!!!

Here in Italy you can't buy magic bullets on Amazon. @chmajovo explained that we can only order those with insane shipping costs and I confirm that.

I tried @LisaK method and it worked wonders for me. I took a regular dulcolax suppository and I waited for about 10 minutes before starting the main enema. It really gave me strong cramps and it was literally uncontrollable after some minutes so yeah… it worked great and really filled my diaper

You might try these folks:

https://farmacialoreto.it

@Sean

They don't carry magic bullets, and they don't ship to Germany, either. What they do have is the Clismasac which seems to only be sold in Italy.

@chmajovo

I don't know about shipping to Germany, but do know they ship to the USA… or at least used to.

If you are looking for a very powerful enema, the Clismasac is surely that They are 2000ml of water plus 100 ml of liquid glycerin. They are apparently designed to completely clean a person out with a single enema. From personal experience, the urge to poo usually starts even before the bag is empty and intense, widespread camping follows very soon. The Clismasac enema is very had to hold.

The camping and pooing continued for quite a while… maybe a half hour or more… after the original explosive poo.

This is not a “comfy” enema, but surely cleans someone out.

@Sean

In my experience, both melted Dulcolax suppositories and crushed pills float on top of the water, and thus will not get where you want them to go. That's why I am interested in the water-soluble variant.

If you soak the tablets in a little liquid castile soap (or other safe soap) the binder will break down and the particles will be wetted. They will slowly settle to the bottom of the enema bag/can, so stir it up before taking your enema if you're waiting more than a couple minutes.

Oil carrier suppositories can be inserted right before the enema if you use a very warm soapy enema (~38 C). The enema will melt and carry the bisacodyl up, but it won't work as well if you don't have soap in it.

I had my wife insert a bisacodyl suppository as far as she could, then I waited about 15 minutes. Then I began to prepare a 3 qt. ivory soap and salt water enema, took about 10 minutes. At this point my wife started giving me the enema, the suppository had been in my body about 25 minutes. She took about 9 minutes to deliver the enema, a lot of mini cramps during the enema. I retained the enema for 4 more minutes, so total suppository time was about 38 minutes. The cramps were getting stronger, I still could resist them, but a little concerned about blowing out the retention nozzle. Started the evacuation, took about 30 minutes, which is really fast for me. Normally, 45-60 minutes to fully release a 3 qt. soapy enema. I then prepared a 3 ½ qt. saline enema, wife gave it to me in just under 8 minutes. During the entire enema, quick little cramps, as more volume was in me the cramps got harder and lasted longer. At the end of the enema, very hard cramps, zero retention, on the toilet immediately. The enema was all out of me in less than 20 minutes, I never had a high volume enema expel that fast, must be residual bisacodyl. Going to repeat this enema in a week or so, after bowel returns to normal.

I’ve done a similar routine with several cleaning enemas then insert the bisacodyl suppository in me, I waited just about 39 minutes before taking the 2 qt soap enema .. lol

I thought I cleaned out pretty good but wow very explosive expulsion which felt great ... finished with rinse enema and clean 👍

My wife is out of town, so it's a do-it-yourself event. I started by taking 3 bulb enemas to clear the rectum, then pushing a generic bisacodyl suppository in as far as I could , then clenching to suck it further up the colon. Waited 20 minutes then prepared a 3 qt. ivory soap enema, 112 F, double balloon latex catheter, and started the enema, knee chest with a slow fill rate. The enema took 10 minutes, so maybe the bisacodly has been in my bowel 35 minutes or so. I laid down on the towel to retain, but a hard cramp came. Got through that, but it got crampy again, I think I could have toughed it out, but I didn't, so on the toilet after maybe 40 minutes. The expulsion was great, kind of contineous, for maybe 25 minutes, then nothing. I waited 10 more minutes then prepared a 3 1/2 qt. salt water enema. Same nozzle, 12 minutes to take the enema, zero retention. The release was very clear, few solids, yellow to light yellow color, amazing ! If you want a complete clean out, this is the process to start with.

Hello,

I have been reading this thread. I am not into enemas sexually but I have medical issues such as chronic constipation I want to resolve.

I have some questions for the experienced people here.

Wouldn't mixing bisacodyl with soap simply trap the bisacodyl in the soap molecules making it unavailable to the colon wall?

Soap is used to clean things, you would think it clean the bisacodyl so your colon couldn't use it.

I broke apart the bisacodyl tablets, soaked them in water for 24 hours and removed the outer acid resistant layer. The bisacodyl doesn't dissolve in the water, most of it just stays on the bottom of the container. How big of a deal is this? Is there a way to make it dissolve into the water?

I want to start with a 2 liter enema. What is the dose of bisacodyl I should use in the enema?

Thanks.

I've used bisacodyl suppositories numerous times with very little success. I usually take 8 or 10 bisacodyl tablets and put them in a measuring cup with about a tablespoon of baking soda plus two cups of hot water. Within 5 or 10 minutes they dissolve completely. I add another two cups of water to cool things off and using a douch syringe send it home. Don't be too far from the toilet because it doesn't take long to take effect.

KY kid, did you mean to say "great success" instead of "very little success"?

You said it wasn't successful then after you said it was very successful.

Also, I am having trouble dissolving them, I hear it doesn't dissolve in water well.

There's always a bit of "sand" particles on the bottom of the container, which I assume is the Bisacodyl.

At the very least I think it should be shook up before you use it, to evenly distribute the mixture.

I've crushed a few tabs with a pair of pliers and then dissolved it in a bit of organic coffee.

Dan

I have melted biscodyl suppositories in very hot water or in a microwave (not on high) until they dissolve in the water they're in. Adding the mixture to a quart or two of plain water into the bag/bucket/bulb delivers the biscodyl more thoroughly and work quite well! Hold time will be brief without a balloon retention nozzle.

Hello,

I have been reading this thread. I am not into enemas sexually but I have medical issues such as chronic constipation I want to resolve.

I have some questions for the experienced people here.

Wouldn't mixing bisacodyl with soap simply trap the bisacodyl in the soap molecules making it unavailable to the colon wall?

Soap is used to clean things, you would think it clean the bisacodyl so your colon couldn't use it.

I broke apart the bisacodyl tablets, soaked them in water for 24 hours and removed the outer acid resistant layer. The bisacodyl doesn't dissolve in the water, most of it just stays on the bottom of the container. How big of a deal is this? Is there a way to make it dissolve into the water?

I want to start with a 2 liter enema. What is the dose of bisacodyl I should use in the enema?

Thanks.

If you're solving a medical problem then you'll want to look at the broader picture and seek authoritative advice. That said I have gotten good advice from here so I will pass on some of my own in the hope it will help.

Mixing bisacodyl with soap doesn't trap the bisacodyl. It would if the soap reacted with it, but it doesn't. In fact I find the soap makes the bisacodyl much more active. This may have to do with making it more available or making the colonic mucosa more receptive to it, I'm not sure.

Bisacodyl does not dissolve in water, so it will remain as a finely dissolved solid. Just give your enema a stir or a shake before taking it and it will work just fine. If you do want to dissolve the bisacodyl I have heard you can use a PEG solution (Mirilax), but I'm not sure it will help much. It will make the enema more isotonic to the colon, but will be noticeably more expensive. I sometimes just soak the bisacodyl tablets in a squirt of liquid castile, seems to work pretty well and after a day there is just a finely divided powder in the soap.

Bisacodyl doses are generally a constant number not a ratio per quart. Start with 10mg, move up to 20 if you need it.

The bisacodyl doesn't dissolve in the water, most of it just stays on the bottom of the container. How big of a deal is this? Is there a way to make it dissolve into the water?

Magic Bullet suppositories contain 10mg bisacodyl in polyethylene glycol, which dissolves readily in warm water. Or you can use them as they are.

Years ago I was given a soap bisacodyl enema in preparation for a barium enema. It did the job very well. After that experience, I routinely prepared 2 qt soapsuds bisacodyl enemas by doing the following: 1. I heated a cup of water to boiling. 2. I added the soap for my enema. 3. I added a bisacodyl suppository and dissolved it. 4. I added the soap and mixture to my nearly filled enema bag. 5. I mixed the added sop and bisacodyl mixture with the water lready in the enema bag. 5. I enjoyed the resulting very thorough enema.

This is a follow up enema to post #196. My wife gave me an enema this morning that started with inserting a bisacodyl suppository. 30 minutes later she started a 3 qt. ivory soap enema w/double balloon nozzle. She took 9 minutes to deliver the enema, so the bisacodyl has been in my bowel for 39 minutes. All reasonably calm until the 42 minute mark, the cramps started, but not too bad. At 45 minutes a lot more cramps and pressure against the inner balloon. I gave in @ 48 minutes, constant cramping, sat on the toilet, wife deflated the balloons, the nozzle expelled immediately. after 25 minutes the enema seemed all out, which is very fast for me, I usually need 45 minutes or more. I waited another 20 minutes, then she gave me 3+ qt. salt water enema to rinse out any residual bisacodyl. 10 minutes to give the enema, 2 minutes retention, then release. What surprised me was that it took over an hour to expel this enema, several return trips, not sure why so long. The rinse enema was relatively clear, the first enema was really effective in removing bowel content.