Miralax Enema

Next month I have to have a colonoscopy, and this time I am only supposed to drink half a gallon of Miralax dissolved in the liquid of my choice. This actually better than the last two colonoscopy preps which required me to drink an entire gallon of GoLytely, the nastiest tasting liquid imaginable. There is no way I am going to go through the cramps, nausea and vomiting again. Miralx has exactly the same Polyethylene Glycol 3350 as the GoLytely, so it will have the same effect.

Back in the late 80s, I had to have a barium enema, and the prep was a laxative, a suppository, and enemas until clear.

My test is more than a month away. so next week I am going to try a test run of the method I am going to use. I plan to go on a liquid diet two days before the exam. The day before the exam I am going to use a Dulcolax suppository early in the morning, and another at noon. Around 4:00 pm, I am going to dissolve the Miralax in two quarts of water, but I am going to use it as an enema. I'll try to hold it for as long as I can. Afterwards, I plan to take 3 quart water enemas until the returns are clear. If I am lucky it will several enemas.

The morning of the exam, I plan to take three more three quart enemas.

As I said, next week, I'll do a test run and see how it goes. Besides, it gives me a good excuse to take enemas, and that's always a good thing.

I'll report back here on how the Miralax enema worked out.

I have had MANY colonoscopies as I'm at high risk for colon cancer. I do not use their recommend preps. I have had a number of comments from my gastroenterologist ‘nice prep’ Also I do not take the meds as I like to see whats going on, the only ‘not so comfortable’ part of that is when he makes the last turn into the ascending colon. I have watched a number of times as he scopes thru the ileocecal valve and into the small intestine. This is easy to spot as the small intestine looks drastically different than the large intestine - the walls have no ‘scalaping’ sorry don't know the proper terms here. I have asked about how my ileocecal valve looks and he smiled and said it looked like it was from someone in their 20's.

My prep:

My partner and I have been doing a weekly top down colon cleans for about 20 years, the only thing I do differently for a prep is use an additional two enemas (4 qts) taken a few hours apart.

I start Friday evening by eating light and having a few drinks. At bedtime I take two Dulcolax laxative tablets, by morning I typically have had two BM's - the second one rather runny. Sat morning is enema time - 1st one is a 3qt taken with soap, I used to use Dr Bronners but have recently switched to OHN's goats milk soap. This is taken and released immediately. Then about 2 hours later I try for a 4qt but only take what is comfy (3.5 ish). Saturday is a juice-fast day - no solid food. Sat evening my partner and I engage in some anal play then about 2 hrs before bed we take another enema or 2 if there is any evidence of solid matter. Sunday morning is the ‘gran finale’ 4+ qts of green tea or chamomile tea taken slowly with a colon tube. When doing a prep, this last step is replaced by taking two enemas in place of the tea enema - I could get away with just one as they are always clear. As a bonus you will be about 5 lbs lighter after peeing out left over water. All my tap water enemas have 1tsp of salt added per qt. I use a 5 qt OHN all silicone bag where I have marked levels at 2, 3, and 4 qts.

I'm not advocating to anyone that they should do this prep for a colonoscopy but it works for me (and Barb).

Adding mirilax to an enema will have little effect mirilax has to go through your digestive system to work as far as I know ,and I take it everyday .

Then again I am the same guy who had to drink GoLytely day and night for 4 days to be empty enough to get most of the colonoscopy in the rear view .

@AquaManH20

I would follow the directions you've been given by your doctor.

Wile Miralax and GoLytely both contain PEG 3350, GoLytely also has other ingredients, including Sodium Sulfate, a powerful but foul tasting laxative. The PEG simply prevents water from being absorbed in your GI tract, so you essentially do a plain water enema by mouth. The volume of solution essentially flushes you out. Also Mirsalax is tasteless.

With the Miralax prep, you are usually instructed to take 4 Dulcolax tablets in addition to the solution. The Dulcolax replaces the Sodium Sulfate to make you poo strongly.

I doubt that Miralax, given as an enema, is going to do anything more that the same amount of plain water. And, taking it as an enema, will do nothing to clean out your small intestine, so poo will continue to come down, resulting in a poor prep.

@SAP Miralax (Polyethylene Glycol 3350 or PEG) acts in your colon by absorbing water which increases the pressure to stimulate the colon to empty itself. Enemas do the same thing, but the doctors use the PEG because it enters the colon at the top and travels the full length of the colon. If a person does not take the enemas correctly they may not reach the very top of the colon where the cecum is.

Using the Miralax in an enema is probably unnecessary, and since i take large volume enemas which fill the entire colon, they flush everything.

@BigJane

“My partner and I have been doing a weekly top down colon cleans for about 20 years, the only thing I do differently for a prep is use an additional two enemas (4 qts) taken a few hours apart.”

I think you mean bottom up, top down would be from the cecum to the anus, which is what the direction Miralax and the other drinks travel.

@Sean Laxatives and the PEG solutions all work in the colon, not the small intestine. Also, if I have been fasting for a day and a half there will be nothing in the small intestine to come out.

I am going to do a test run next week to see if my colon will be clean. I am going to verify it by taking a large enema the evening that the test would have taken place. If the water is clean, then I know my colon would have been clean for the scoping.

The doctors insist on forcing the tortuous PEG drinks on us because there is no question it travels the full length of the colon, while a person taking an enemas, if done incorrectly, may not flush out the upper part of the colon. I looked online, and found a clinic that uses enemas for prep. They require three enemas the night before the test, and three more the morning of the test.

@BigJane Would you and your partner consider letting a man join you. Heck, I'll even be submissive and you can dominate me.

Regarding the thread, when I mentioned ‘Top Down’ we do typically start Friday evening taking two Dulcolax laxative tablets, and after morning enemas the next day, that day itself is a juice-fast day followed by more enemas so I do believe we are doing ‘Top Down’.

Regarding company - I don't know about that. Barb and I are not into the domme thing so much as mutual pleasure. I'm sure you have guessed that i'm the Top however.

We actually take most of our enemas solo except when assisting a partner with a colon tube.

Miralax between rounds, in a cleansing, seems to work.

Well, I did a couple of rounds of Miralax enemas. I found the recipe from a medical research study which used Miralax taken orally and by enema to break up fecal impactions. The recipe is 4 doses (capfuls) per quart. CVS pharmacy had their store brand on sale, buy one get one half off for 50 dose bottles, that is enough to make 25 quarts.

On to the enema. I took three quarts and held it for 10-minutes. I was able to take the 3-quarts more easily than plain water, and it was easier to hold. The expulsion was less irritating than plain water. I followed it with two more 3-quart Miralax enemas. Since I had not fasted, fecal matter continued to enter my colon and for the next few hours I was constantly running to the toilet to expel soft almost diarrhea-like feces. I realized that I definitely need to take a couple of clear water rinsing enemas to remove the Miralax.

By the way, I found three medical research studies that used Miralax in enemas. One was a comparison of different enema solutions. Miralax provided the worst results, Soap enemas came in second, and the dreaded Milk and Molasses did the best job cleaning the bowels.

I decided to try something different. Aloe Vera enemas. I bought a large jug of Aloe Vera Juice from Amazon. The recipe is four ounces per quart. This enema was easier to take and I was able to take four 4-quart enemas, and, after the fourth enema, for the first time ever, I took a 5-quart enema. Every time I started to shut it off, I forced myself to hold on for a little while longer, until finally I heard the satisfying sucking sound as the last of the enema water drained from the bag. Luckily I decided to do it in the bathtub because the enema exploded from my butt a soon as I removed the nozzle. I would never have made it to the toilet. I must have expelled close to 2-quarts before I could safely move to the toilet, and even then, I barely made it before the torrent started again.

Let me tell you about a great enema bag that holds 5-quarts, strong and sturdy, see through so you can see the enema solution as it drains into you, and economically priced.

TopQuaFocus Large Enema Bag 4 Quart at Amazon, for $28.99

www.amazon.com/gp/product/B08BJLLXP4/ref=ppx_yo_dt_b_asin_title_o07_s00?ie=UTF8&psc=1

If you fill it to the neck, it actually holds 5-quarts, and to the tippy-top, almost spilling out, it is just 2 ounces short of 5-½-quarts.

It is silicone, has two reinforced eyelets, so you put the hook through both which reduces the chance they will tear out of the bag.

There is a regular large ramp/snap clamp, and a nice adjustable valve. The nice thing about that is that if you adjust the flow rate and have to stop for cramps, you can use the ramp clamp to stop the flow so that when you resume, the flow rate is the same. It has a stainless steel S-hook large enough to fit over a towel rack with plastic tubing over it to protect it. The bag comes with four nozzles, and a nylon backpack so you can carry your enema bag on your back (or chest if you have a regular backpack on your back) when you go camping and no one will know what is in the backpack. LOL

Her: “Hey honey, why don't you unpack your backpack.”

Me: “Okay dear, look what I packed, it's time to bend over that tree stump and take your enema right here in the woods.”

Her: “Sure honey, give me 4-quarts of that cold stream water.”

Me: “Not today, today you get 5-quarts with this Double Balloon Nozzle.”

Compared to other bags in the price range and the overpriced bags at $80 to $100, this is a real bargain for a great bag that holds as much enema as most of you normal people will ever need (not counting the bullshitters who claim to take 7, 8, or more quarts at a time). The only negative is that it is made in Communist China, our sworn enemy, and I hate sending money to the Commies!

I have another cheaper red bag that also holds almost 5-quarts, so I am beginning to think they may be talking about Imperial Quarts (Old British unit) which are 20% larger, in other words 4 Imperial Quarts would be 4.8 US quarts.

Just wondering what the general quantity of MiraLax to a quart of water is used. I've tried this before and want to give it a try. Any info would be greatly appreciated. Thanks all

The directions on the bottle say 17 grams to 4 to 8 oz of liquid. You could go with the 4 oz with 17 grams, So 136 grams to a quart, or 8 capfulls to a quart of water. You drink that and you will get cleaned out for sure.

I believe that you are better off to drink the Miralax and use something like baking soda mixed in the water for an enema. Miralax as an enema could get really expensive, baking soda and some salt are much cheaper.

Miralax is an osmotic agent and prevents the absorbing of water from the GI tract. Hence, if you drink a bunch of it, the water stays in your tract and eventually softens the poo and makes you poo, akin to the way an enema does, by filling your colon with fluid. The hefty dose of Miralax, given for colonoscopy preps, acts essentially as a 2 to 4 quart enema, given top down.

I have thought that adding Miralax to a very slowly given, long retained, enema might be useful in softening hard poo, without overloading the recipient's body with excess fluid.

I'm not a medical professional but I think Miralax in an enema will be quite ineffective as it is designed to increase the water in your bowel from top down. It may clear out the lower colon but will be no good at upper bowel cleansing. My 2 cents.

@Moppys_jalopy

I never said Miralax in an enema will clear out someone's bowel. I only said Miralax, in a long retained enema, should soften poo and prevent water from being absorbed from the colon into the person's body.

@Moppys_jalopy

I never said Miralax in an enema will clear out someone's bowel. I only said Miralax, in a long retained enema, should soften poo and prevent water from being absorbed from the colon into the person's body.

Ok. I stand corrected. I just think it is a waste of good Miralax.

PEG3350 (Miralax and myriad other brand names) enemas are not uncommon when treating impaction.

@Victoria1951

Interesting. I suspected as much for the reasons I stated, but do you have references to what is actually done?

I take one dose of 17 gram Mirilax daily and three 40 ML doses Of lactulose 1 hour before each Meal , this is a “top down enema “ you can not stop what’s going to happen( or you can try and lose it much sooner , the only think that combo enjoys more is someone denying the need to use the bathroom and it forcing you ) I don’t have any sensation to respond to , so it decides when I will go for me . If you use recreational enemas taking it orally will negate the need for them .

Interesting. I suspected as much for the reasons I stated, but do you have references to what is actually done?

Search the term: “peg3350 enema impaction”. There will be multiple links to studies that present differing combinations of enemas and oral laxatives. In a few studies, naso-gastric tubes are used to feed a drip of PEG-3350. In a few studies oral lactulose was used with PEG3350 enemas. That is one combo that you do not want to be downrange when it acts.

@Victoria1951

Yes, I am well familiar with giving PEG3350 orally, more slowly than for a bowel prep, perhaps through a NG tube , to relieve an impaction and can well believe giving PEG for several hours to soften poo, followed by PEG3350 and Lactulose to completely clean out the person will produce dramatic results. A full dose of Lactulose alone is a very potent, fast acting laxative.

I didn't find any references to PEG33650 solution used as an enema.

@Sean

https://www.cancer.gov/publications/dictionaries/cancer-drug/def/polyethylene-glycol-3350-containing-enema-ner1008

https://www.researchgate.net/publication/322204765_Efficacy_and_Safety_of_Combined_Oral_and_Enema_Therapy_Using_Polyethylene_Glycol_3350-Electrolyte_for_Disimpaction_in_Pediatric_Constipation

@Victoria1951

Thank you. It's interesting others have thought of the same ideas, but it's not been widely used or studied.

It's interesting others have thought of the same idea, but it's not been widely used or studied.

My guess is the researchers are looking for a replacement for Lactulose and Bisacodyl. PEG3350 is not a stimulant like Bisacodyl nor a gas generator like Lactulose. The latter two are noted for causing painful explosive aerosolized results when clearing impactions that often require cleaning of the patient, bed, room surfaces, walls, floors, visiting family members and staff.

Peg 3350 or Mirilax if timed with Lactulose , lactulose speeds up Mirilax effect . Mirilax and Lactulose at low dose say up to 3 days before action which is probably legit , however with a high dose of lactulose that produces effects within two hours is dragging water and PEG into bowel at same time thus increasing the PEG ability to draw water into bowel and produce synergistic rapid effect without waiting up to three days , in other words you should always drink water before and after( osmotic agent ) to enhance action, lactulose dose that Water has PEG in it before and after before straight water is not going to have any delay in taking effect as the Lactulose is going to be an accelerant . You could expect a very dramatic effect with very volumous soft Stools and probably pass some brown water after exhausting your actual fecal waste . I strongly urge you to be wearing appropriate diaper and plastic or rubber pants with additional protection for bed and chair you will not have a toilet option unless you want to spray poo around your house and get to toilet and find your done .

the difference between farting and filling will be sudden and “violent“ . For any ABDL who has wanted to experience “ no control , incontinence “ this will be that ,no question in my mind or experience your job is to be taped up and hang on , of course some lite excercise after taking it will enhance digestion which will enhance how rapid Onset ( gas) and how hard you fill the diaper will be after a little excersise I suggest you get comfortable in your favorite position and Relax take a nap let nature take it’s course , if you do fall asleep you will not miss anything your brain will wake you in time to bear witness to your unrelenting no brakes freight train about to come out of butt crack pass , you will only be an observer and an eventual clean up crew , what is supposed to happen will , you have no ability to intervene , inter fear or prevent the filling of your diaper . Let us know how you liked it , did it feel the way you imagined or expected ? If you have a device almost everyone does ,use the stopwatch function to see how long till onset of gas and then till diaper filling ,it can vary from person to person but it will happen , your body has no other choice as the medication is controlling it , your bowel Has no experience with a medication that takes total control , even people who use daily laxatives or enemas to promote emptying your body still has a vote and ability to say excuse me I am in control here ! This combination ignores your body’s claims of control and substitutes it’s own control that you rapidly and substantially fill whatever your wearing .

in my experience taking these there is no gripe or abdominal discomfort like high doses of bisacodyl or other stimulants

there is no variability in stool consistency from diet or other factors .

there is no unexpected urgent false alarms or potty calls later . When it acts you are done ( for me taking divided doses and eating as Expected results in multiple required acts of diaper decorating )

there is a split high dose regimen that treats a very dangerous uncommon medical condition, only problem is that dose causes profound incontinence with near constant anal leakage , people go to doctor or emergency room and on discharge find themselves in a commited relationship with adult diapers and soiling themselves 24/7 randomly .

The reason for Lactulose being so effective and not habit forming is it’s a synthetic sugar the human body has no ability to absorb or metabolize it so it is always sent to bowels alone with a lot of water , where the gut bacteria try to break it down the gut bacteria break it down into three main cases that’s where the farts come from , and some laxative compounds that combine with all the water being dragged into bowels that softens stool and increases size , so the laxative compounds compounds are constantly forming with the gas ,as the swollen softened poo is booking along your bowels , the more gas the more laxative compounds build up NS that triad of effects just keeps increasing until it is expelled ,which is why try to resist expulsion plays right into its hands giving it more time to build gas create laxatives and pull stool into rectum , unless you have incredibly dry hard stool that you can’t pass all of the above actions are going to climax in your rectum and create the unstoppable urgent need to fill your diaper with every bit of well lubricated well hydrated stool it’s been pushing down since it left your stomach you will not be able ”to pinch it off “ or exert any control until the medication and stool are forcefully and completely expelled no more gas building no more laxative building no more pushing stool to rectum , everything goes back to “normal “ in your case , for me I have taken my next normal scheduled dose and am eating so that entire cycle of Cause ( my aide puts a soft oral syringe in my mouth that has my dose and Slowly injects as I swallow )and effect ( my aide changes my filled diaper and depending on timing my insert my urethral catheter to remove the stale urine building up in there ,whatever urine not lost to the diaper is building up for a sneaky tsunami catching 5 ax’s a day substantially reduces dynamic events requiring an immediate change .

4 does of Mirilax at same time before each meal causes osmotic diarrhea .

17 doses mixed in 1 bottle of Gatorade results in the purge . Repay that again 1 time and most people are cleaned and ready for colonoscopy .

in studies of volunteers eating the same measured diet and half were induced osmotic diarrhea with Mirilax and half with lactulose is very interesting study and yielded lots of information about organic diarrhea snd substance induced diarrhea the PDF study comparisons and results are on google if you should be moved to read it .

As to Miralax enemas, here is my thinking

The purpose of a Miralax enema is not to cause an immediate response. Their purpose is to hold water, or more correctly the PEG solution, in the person's colon for an extended period of time, with the objective of softening and hydrating hard poo, s that when the urge does happen, passing out the hard poo becomes easy. My guess is the solution should be held for an hour or more. The reality is it takes time to soften hard poo. Without the PEG, the enema water will be absorbed into the person's body.

So, if I were going to do this, I'd either give the enema slowly, perhaps a 4 Oz bulb every 15 minutes so as not to cause an urge to poo, or perhaps set up a bag with a flow control, to allow drip-by-drip inflow, connected to a Foley catheter to aid retention. I'd take the solution over several hours.