What Causes Peyronie's Disease?
Doctors don’t know exactly why Peyronie's disease happens. Many researchers believe the fibrous plaque can start after trauma (hitting or bending) that causes bleeding inside the penis. You might not notice the injury or trauma.
Other cases, which develop over time, may be linked to genes. In some men, injury and genes could both be involved.
Some medications list Peyronie's disease as a possible side effect. But there is no proof that these drugs cause the condition.