Docusate sodium

The main ingredient in Enemeez mini enemas is ducostate sodium 283 mg.

It usually works in 2 or 3 minutes and is a good start to large volume enemas.

It is sold as a stool softner in gel caps.

I was able to purchase 16 Oz's of dioctyl which contains 50 mg of ducosate sodium per 50 ml of solution.

Doing the math, I injected about 30 ml of dioctyl.....no need to evacuate?

"Solutions to the solution are welcome!

I purchased this product thru Amazon for about $6.

Joymkr

The main ingredient in Enemeez mini enemas is ducostate sodium 283 mg. . . . .

I was able to purchase 16 Oz's of dioctyl which contains 50 mg of ducosate sodium per 50 ml of solution.

Doing the math, I injected about 30 ml of dioctyl.....no need to evacuate?

"Solutions to the solution are welcome!

I purchased this product thru Amazon for about $6.

Joymkr

1--283mg is about 40 mg more than a standard 240/250 mg dioctyl gel cap.

2--you bought 16 ounces of dioctyl which has 50 mg per 50 ml, so doing the math as you say, that's one mg per ml, or in the pint you bought 473 mg dioctyl, which is just about 4-5 lower dose gel caps and doing more math, 30 ml is 30 mg, which is one third to one eigth of a dose.

3--If the numbers you gave are accurate, YOU GOT RIPPED OFF BIG TIME.

It sounds to me like you bought the syrup form of dioctyl sodium sulphosuccinate. It is red in color and is intended for kids, or adults that can't swallow caps. It is much milder than the "liquid" form of the chemical. I sold all forms of it under the brand name, Colace. The more potent form is packaged in 10 ml. bottles with an eye dropper. This is intended for babies to drink in their formula; the mom puts however many drops in it that her pediatrician instructs. The other use for Colace Liquid is to add to small retention enemas, usually Fleet type products. We'd tell the physician to pour out a few ml. of the enema solution and fill it back up with Colace Liquid to use in hard stools, instead of mineral oil.

Docusate sodium is a detergent and it makes water 'wetter", thus penetrating the oily mass that feces in comprised of. The oral syrup is packaged in 16 oz. bottles and is dosed in teaspoon size dosages. Maybe if you put an entire pint bottle of the syrup in your bag, it might work.

But really, how well does something intended to be taken orally work when taken rectally? This sounds like putting the product in via the wrong orifice.

Docusate rectally can be surprisingly potent. The question is how concentrated is it, and how much was given. Docusate dissolves the mucous that normally coats the bowel lumen. That more directly exposes the nerve endings in the colon. The result is nerves are in direct contact with whatever is in the enema, and they get much more stimulation. In Australia they used to sell a highly concentrated solution of Docusate, It was diluted about 20:1 for use in enemas. Such enemas usually contained several grams of docusate, and most people would find such an enema extremely difficult to hold for any length of time, so docusate can be a very effective bowel evacuant.

Those wishing a truly moving experience might try dissolving 10-12 250mg docusate capsules in a liter of water. No need for anything else in the enema except the docusate,

Mattheww, Thanks for the detailed explanation as to how docusate works when injected rectally. I sold that product for 14 years and never knew it worked the way you describe. That would explain what one of my Doc's told me about it, as part of a Fleet: He said he had told one of his patients to pour a little of the Fleet out and then refill it with several grams of Colace liquid and take that. The patient told the Dr. that he could hardly make it to the commode, the stimulation was so strong. This stripping of the mucous membrane, exposure of the nerves, coupled with the sodium phosphate would give a strong stimulation immediately .

. . . . This stripping of the mucous membrane, . . .

It NOT stripping the MUCOUS MEMBRANE.

It is removing the MUCUS coating the colon tissue surface.

MUCOUS MEMBRANE is not MUCUS coating.

A mucous membrane is a type of tissue.

MUCUS is the exudate covering the surface made by a mucous membrane

Thanks for being so observant SwitchableSusie!

I misstated the ml relationship in my post. The corrected proportion is 50 ml of docosate sodium to 5 (not 50) of other liquid

Nonetheless, even at that ratio, 30 ml of dioctyl would approximate just 1 gelcap.

I will try increased dosages and post results.

Thanks to all who responded to this post.

Joymkr

Docusate rectally can be surprisingly potent.

You're absolutely right. I tried the 5 gram in 2 quart dose, and it was a very thorough cleanout in 15 minutes or so (counting expulsion!). While very powerful it didn't seem to upset my stomach quite as much as an (seemingly) equivalently strong peppermint castile solution, and the the expulsion seemed to go faster (sometimes I get what seems like slightly uncoordinated peristalsis with strong soapy solutions, so I can feel my gut trying but not as much gets out). Note that that might just be "luck" because I've only done one of these.

I used the gel capsules (50 of the 100mg types!) I had them on-hand because at one point it was recommended that I take metamucil, Mirilax and docusate (off topic note - is there a point to the docusate if you're already taking Mirilax?). Soaking the capsules overnight in cold water and squeezing seemed to work OK, but when I put warm water on them they dissolved into a blob of gelatin. Hot water might dissolve them completely.

I'm thinking about putting this in my "menu" to deal with constipation. It would definitely be with the stronger solutions (Mayo, bisacodyl and soap), but I think I like it better than strong soapsuds. I'd still likely keep the light SSE and tap water as the usual go-to enema, but for when I'm more backed-up or my bowel isn't cooperating I'd definitely go for the docusate again. Maybe try a 2.5gram in 1 liter dose taken as a multi-position enema to see if that works well enough with less docusate.

If I was to put this in my "menu" I think I'd look for a liquid or solution so I wouldn't have to mess with the capsules, but the ones I found seemed to be all weak (50mg/5mL), which would be expensive and difficult to manage. Even looking for dioctyl sodium sulfosuccinate didn't pop up much, so I'm not sure how best to find this.

Note to mods - could the title spelling be corrected?

Moliere, you should be able to find everything you need online. We are talking about docusate sodium liquid solution 50 mg/5ml. There are various generic versions of it available from the online medical supply stores. This is the same formulation as the old Colace liquid that was once available in the laxative aisle of most pharmacies. I have not been able to find it in a retail brick and mortar store for years, though.

Up until about 20 years ago, the Colace liquid packaging actually had dosing instructions for both oral and enema administration. That is how I learned that it could be added to an enema. Enema dosage was 5 to 10 ml added to one quart of warm water. I typically used 10 ml added to 2 quarts. After I could no longer find Colace liquid in pharmacies, I stopped using it until I found the generic version online a couple of years ago.

I think the Colace should continue to work quite well for your constipation. When I am seriously backed up (5 days or more), I use 10 ml of docusate sodium in an enema and get an amazing cleanout. I actually think it is more effective than a strong soapsuds solution. I can completely evacuate in 15-20 minutes as opposed to 30 minutes plus for plain tap water. Plus, it has a very pronounced softening effect - something you appreciate if you are actually suffering from constipation. I do have some residual cramping later in the day which maybe from irritation of the colon lining. I am not sure that I would use the Colace for purely recreational enemas.

Moliere, you should be able to find everything you need online. We are talking about docusate sodium liquid solution 50 mg/5ml. There are various generic versions of it available from the online medical supply stores. This is the same formulation as the old Colace liquid that was once available in the laxative aisle of most pharmacies. I have not been able to find it in a retail brick and mortar store for years, though.

Up until about 20 years ago, the Colace liquid packaging actually had dosing instructions for both oral and enema administration. That is how I learned that it could be added to an enema. Enema dosage was 5 to 10 ml added to one quart of warm water. I typically used 10 ml added to 2 quarts. After I could no longer find Colace liquid in pharmacies, I stopped using it until I found the generic version online a couple of years ago.

10 mL in 1 quart is easily doable, but only 100mg of docusate. I guess I can try that out and see what happens, but all the recipes I've seen have been 2+ grams per liter, which works out to a much less doable 200mL of docusate solution per quart/liter. 100mL would also be one of the capsules, snip and squeeze becomes much easier with only a few.

I think the Colace should continue to work quite well for your constipation. When I am seriously backed up (5 days or more), I use 10 ml of docusate sodium in an enema and get an amazing cleanout. I actually think it is more effective than a strong soapsuds solution. I can completely evacuate in 15-20 minutes as opposed to 30 minutes plus for plain tap water. Plus, it has a very pronounced softening effect - something you appreciate if you are actually suffering from constipation. I do have some residual cramping later in the day which maybe from irritation of the colon lining. I am not sure that I would use the Colace for purely recreational enemas.

You are definitely right about the docusate, at least at 5mg/2L. It's a "go in and get things done" enema and works very well for that. As recreational enema, probably not unless you're seeking cramps and a big urge. With a retention device, a stern partner, and a timer it could be a very effective punishment enema. Mine was wanting out big-time within 5 minutes, and I was more than happy to let it leave.

I guess what I experienced later on could be called cramping, though I experienced it more as grumbly and active bowels. It went away over the next hour or two and didn't cause a problem with doing what I needed to. I imagine a lower dose of docusate would be even fewer effects.

Given how docusate sodium works on the mucas in the colon, and how bisacodyl works, does anyone have any experience with an enema that has both agents in the enema??

I've done soap and bisacodyl, and that works very well. I tried a small enema with docusate and bisacodyl mixed up in a Fleet bottle, but I left in some of the phosphate solution. Something reacted with the bisacodyl and reduced the effectiveness substantially, my guess is that it was the phosphates.

Give it a try and let us know.

I took an enema consisting of 400 mg of docusate sodium, 20 mg bisacodyl, and 1 tbls bronners peppermint, total volume about 2 1/4 quarts. 6 minutes to administer the enema- with double balloon nozzle- after about 7 minutes of retention, the cramps were heavy, so i released the enema. most of the enema was gone after about 10 minutes, so it expels fast. the addition of the docusate makes the bisacodyl/soap enema more intense, faster to cramp, and harder cramps.

Might need to try that TRW.

This is good stuff. I dissolved 10 of the 250 mg softgels in a cup of warm water then used that to make a quart enema. A little stronger than I would have wanted with effects that were lasting until the next morning. Once I narrow down on the right strength (probably about half of what I used) I think this will be my favorite enema solution second to glycerin.

Yeah, the 5 gm/Liter concentration would be KILLER!

Along with you I found the 2.5gm/L dose to be a bit strong even. TRW's dose sounds more doable.

If i use just docusate sodium in the enema, i use 600 mg. in 2 1/4 quarts of water , even with a double balloon catheter, it's a struggle. 10 minutes after starting the enema, the cramps will get your attention, how long you want to continue is up to you, but i'm done @ 12 minute mark. a positive aspect of the docusate enema is that it's all out of you in 10-15 minutes, no return trips.

Have to try the 600 in 2.25 quarts. 2.5 Gm/liter definitely had after effects that lasted a while. Would like a speedier recovery.

Docusate sodium enemas are tough on latex tubing, after a few, you might want to change the tubing.