Enemas and Depression

Anybody else find that enemas help combat depression. I was diagnosed years ago and take medication. I still get panic attacks. I've found that enemas take my mind off my problems by providing an intensely pleasurable experience that always provides a great lift to my mind, body, spirit ✨️.

You could say they depress the shit out of me…….

Yes, I find they’re a good stress reliever, and although they’re a bit crampy, once it’s all over I feel whole lot fresher and less anxious. Although usually the effects don’t last that long.. maybe 24 to 48h.

I took an enema once because I was in a bad mood. It help put me in a good mood. I also find that taking a laxative, such as Milk of Magnesia, will put me in a good mood.

I have found enemas to definitely help with depression. I had depression after my wife passed and laying in a tub of hot water and enjoying an enema ....I always was better afterwards.

It is one of the very few things that can get me out of my head so to say.

Therefore one of the things that can bring me some mental peace.

(ASD, ADHD, cPTSD)

I don’t have medical defined depression, but whenever I have one of those days when I just feel shitty for no apparent reason, nothing improves my attitude quicker and better than a good enema and an orgasm. Best medicine you don’t have to buy.

An enema usually blocks out everything else except what I’m feeling in the moment, and it can be blissful. It’s sort of an oasis of the mind. It really does help relax me if I’m over-stressed, which seems more often lately. I definitely feel better emotionally after an enema.

I don’t suffer from “medical” depression, but I do feel down with the blahs when I’m backed up. My family can tell when I’m grumpy. My daughter is the first to tell me, “Mom, you need an enema!”

For me an enema can be an emotional reset button. If I am feeling down quite often an enema is exactly what I need.

I've been enjoying enemas for decades. While I don't have diagnosed medical depression, I've found that my mood is definitely elevated during and after an enema. I can think of many times when I was feeling sad, down, stressed, anxious, etc. A slow, sensual enema always seems to help. Words like soothing, calming and comforting come to mind when I think of how much better I feel during and after an enema. That probably has something to do with how I felt during my first enema and how much better I felt afterward (my story can be found in other discussions). Most of the time I've done this solo but sometimes I'll call one of my phone girls for some guidance and to enjoy some talk therapy during a mood-elevating enema. It's wonderful to share that experience with a compassionate listener who understands and supports / coaches me through the treatment.

If you feel that an enema helps you with your depression, then an enema helps you with your depression. The trouble with mental health care in the U.S. is that all diagnoses are made on nothing more than a statistical probability, with guidance from the Diagnostic Statistical Manual (DSM-5). Also, we have a pedagogical/corporate healthcare system that, by design, is created to disregard individual feelings and preferences towards managing diseases, particularly mental illness, and lump everyone together without considering the overall milieu of those who are very comfortable with enemas.

There is some emerging evidence that would theoretically support the idea of enemas potentially helping with depression. They have found that there are far more cells that are responsible for the production of endorphins (which regulate mood) in the intestine, than in the brain, which would mean that an unhealthy, unbalanced gut could cause mood disorders and depression. So, if enemas are removing toxins from the colon, and improving gut health, you could surmise that enemas could potentially help with depression in some patients.

The June 2026 edition of American Nurse features an article, "Microbiome and Depression." The article discusses the connection between the gut and the brain, as well as the bacteria, fungi, protozoa, viruses, and other microorganisms that make up the microbiome. Of note, it also mentions the tremendous amount of endorphins produced in the gut and covers neurotransmitters and brain function. The article does not specifically mention enemas because if it did, this article would not be published because it would not pass pedagogical peer review. Also worth noting for those concerned about destroying bowel bacteria, virtually all studies point out that post-bowel prep for a procedure such as a colonoscopy, there is full biodome recovery within 7-14 days, and points out that not all of the bacteria are destroyed during bowel prep, i.e., the bowel is not made sterile, and that a round of broad-spectrum antibiotics is much more devastating to the microbiome than routine bowel prep. Our enteric nervous system is, in reality, one big pleasure dome, producing many endorphins that may not produce full-blown orgasmic pleasure, but it is knocking on the door. Simply stated, we love to eat, and we love to poop. That is to say, we all love that little extra shot of whipped cream on the pie and having a successful bowel movement. So, in summary, and as I mentioned previously, if you think enemas help with your depression, then they help with your depression. Granted, for most, this may not be the case, but I think it is important to recognize that many of us who frequent this website are very comfortable with enemas and have used them for pleasure for many years; it is a strong part of who we are.

Compared to other things people get into, an enema is clean fun.

Here is the link to the article I referenced several weeks ago:

https://www.myamericannurse.com/microbiome-and-depression/

An incredibly interesting article.

A good clean out always improves my state of mind, I feel so calm and relaxed afterwards and that all is good in the world. It’s been that way since I started taking enemas as a kid and remains the same today, being anal retentive is not a good thing. As for gut flora, I have been eating a yogurt every day for the last few months to help my gut and I can say I feel a little better overall and have noticed a definite improvement in my skin and that makes me happy too.