Pain relief enemas

So I was looking at my little box of paracetamol that I have been using for the past few days and got curious. Would dissolving these in water and taking them as a small enema injection have the same effect as taking it orally.

I know I know, suppositories if these drugs exist, but the pharmacy was all out of those. So I had to take these ones.

I have no specific reason to want them up my ass other than that it's just fun.

These pills are advertised as dissolvable in water so that you can take them that way, but not sure if squirting that water up my bum would have the same effect.

Welp, hopefully someone has some insights on this. Or maybe someone knows some other pain relief or anti inflammatory enema solution.

Thx!

Please be warned that Paracetamol is quite toxic. I wouldn't recommend use it in any way in any situation but extreme one.

Theoretical, if there is a suppository with some active ingredient, you can make enema solution with it. In general, suppositories are oil-based, making them not water-dissolvable. Which leads to use some water-based oral equivalent.

I wouldn't try this. But if you wish so, please doublecheck that dosage of active ingredient will not exceed it in analogous suppository, and that supplementary ingredients in your product will not harm you (allergy, diabetics, etc.).

One more thing. Without pre-cleanout enema the enema with active solution can be much less effective.

Where I live (Netherlands) paracetamol is basically the go to pain relief and anti inflammatory drug. It's sold everywhere and everyone has a pack at home so I didn't know it was toxic.

The suppositories containing it usually go up to 1000mg.

It sounds similar to aspirin. I’m not a doc or pharmacist so I’m not recommending that you try it in an enema. It does come in supossitory form as well, you might look for that and ask a pharmacist if the capsules are different chemically than the suppositories

https://www.mediclinic.co.za/en/infohub-corporate/healthy-life/paracetamol-vs-aspirin-your-essential-guide-to-more-accurate-pa.html

@Rigel I just googled it and aspirin is a brand name for paracetamol with a bit more stuff mixed in, at least that's what it is here.

So Google says that Aspirin has the extra stuff in it so that it works anti inflammatory. Paracetamol does not and so I've taken one for nothing.

Ibuprofen however does work anti inflammatory (or at least Google says) and I've found studies stating that it gets absorbed faster through an enema than through a suppository.

Unfortunately I can't find how to make said (micro)enema 😢

I Just received my beloved Coffee enema. I cant slept any more and I got headache. Feeling so good with two Liter of Green Coffee in my stomatch. Holding it already for 45 minutes...

I tried this once using a Vicodin with less than satisfactory results. I crushed and dissolved the pill but it was a waste of a pill. The enema was good (as always) but I felt almost nothing from the Vicodin after holding it for as long as I could.

If I were crushing a pill, I would use only a very small amount of water so it would be absorbed stronger in the rectum.

Dan

Paracetamol is a brand name like Tylenol, whose generic name is acetaminophen. It comes in suppository form, but I do not think I would use the medication as an enema. I am not sure it would even be effective.

For a headache I used to dissolve a couple aspirin tablets in my enema water and hold it for a while. I later heard that aspirin in the intestine could cause bleeding so I stopped the procedure. I seldom get headaches anymore, but if I do, i go the oral route. So is it harmful? The hoseman